Mollusc-Derived Brominated Indoles for the Selective Inhibition of Cyclooxygenase: A Computational Expedition

Mollusc-Derived Brominated Indoles for the Selective Inhibition of Cyclooxygenase: A Computational Expedition

Inflammation plays an important role in different chronic diseases. Brominated indoles derived from the Australian marine mollusk <i>Dicathais orbita</i> (<i>D. orbita</i>) are of interest for their anti-inflammatory properties. This study evaluates the binding mechanism and...

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Bibliographic Details
Main Authors: Md. Mominur Rahman, Md. Junaid, S. M. Zahid Hosen, Mohammad Mostafa, Lei Liu, Kirsten Benkendorff
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Molecules
Subjects:
<i>Dicathais orbita</i>
inflammation
COX-1/2
molecular docking
molecular dynamics
drug-likeness
Online Access:https://www.mdpi.com/1420-3049/26/21/6538

Internet

https://www.mdpi.com/1420-3049/26/21/6538

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