The EMT transcription factor Snai1 maintains myocardial wall integrity by repressing intermediate filament gene expression

The EMT transcription factor Snai1 maintains myocardial wall integrity by repressing intermediate filament gene expression

The transcription factor Snai1, a well-known regulator of epithelial-to-mesenchymal transition, has been implicated in early cardiac morphogenesis as well as in cardiac valve formation. However, a role for Snai1 in regulating other aspects of cardiac morphogenesis has not been reported. Using geneti...

Full description

Bibliographic Details
Main Authors: Alessandra Gentile, Anabela Bensimon-Brito, Rashmi Priya, Hans-Martin Maischein, Janett Piesker, Stefan Guenther, Felix Gunawan, Didier YR Stainier
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-06-01
Series:eLife
Subjects:
cardiac development
cell extrusion
tissue integrity
Online Access:https://elifesciences.org/articles/66143

Internet

https://elifesciences.org/articles/66143

Similar Items