The EMT transcription factor Snai1 maintains myocardial wall integrity by repressing intermediate filament gene expression
The transcription factor Snai1, a well-known regulator of epithelial-to-mesenchymal transition, has been implicated in early cardiac morphogenesis as well as in cardiac valve formation. However, a role for Snai1 in regulating other aspects of cardiac morphogenesis has not been reported. Using geneti...
Main Authors: | Alessandra Gentile, Anabela Bensimon-Brito, Rashmi Priya, Hans-Martin Maischein, Janett Piesker, Stefan Guenther, Felix Gunawan, Didier YR Stainier |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2021-06-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/66143 |
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