FOXC2-AS1 regulates phenotypic transition, proliferation and migration of human great saphenous vein smooth muscle cells

Abstract Objectives In varicose veins, vascular smooth muscle cells (VSMCs) often shows phenotypic transition and abnormal proliferation and migration. Evidence suggests the FOXC2–Notch pathway may be involved in the pathogenesis of varicose veins. Here, this study aimed to explore the role of long...

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Bibliographic Details
Main Authors: Chuang Zhang, Huixiang Li, Xueli Guo
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Biological Research
Subjects:
Online Access:https://doi.org/10.1186/s40659-019-0266-z