Whole genome sequencing identifies loci specifically associated with thoracic aortic wall defects and abdominal aortic aneurysms in patients with European ancestry

Whole genome sequencing identifies loci specifically associated with thoracic aortic wall defects and abdominal aortic aneurysms in patients with European ancestry

Objective: The objective of this study was to better understand the pathophysiology and underlying genetic mechanisms behind two abdominal aortic aneurysm (AAA) subtypes using computed tomographic imaging in combination with whole genome sequencing. Methods: Patients with a known AAA and European an...

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Bibliographic Details
Main Authors: Grace H. Miner, PhD, Alan E. Renton, PhD, Ella Taubenfeld, BS, Rami O. Tadros, MD, Edoardo Marcora, PhD, Robert A. Lookstein, MD, Peter L. Faries, MD, Michael L. Marin, MD
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:JVS - Vascular Science
Subjects:
Abdominal aortic aneurysm
Genetic association
Aortic dissection
Genetics
Morphology
Online Access:http://www.sciencedirect.com/science/article/pii/S2666350320300225

Internet

http://www.sciencedirect.com/science/article/pii/S2666350320300225

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