Improving Radiation Response in Glioblastoma Using ECO/siRNA Nanoparticles Targeting DNA Damage Repair

Improving Radiation Response in Glioblastoma Using ECO/siRNA Nanoparticles Targeting DNA Damage Repair

Radiation therapy is a mainstay in the standard of care for glioblastoma (GBM), thus inhibiting the DNA damage response (DDR) is a major strategy to improve radiation response and therapeutic outcomes. Small interfering RNA (siRNA) therapy holds immeasurable potential for the treatment of GBM, howev...

Full description

Bibliographic Details
Main Authors: Jennifer A. Lee, Nadia Ayat, Zhanhu Sun, Philip J. Tofilon, Zheng-Rong Lu, Kevin Camphausen
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Cancers
Subjects:
nanoparticles
siRNA
glioblastoma
radiation
DNA damage repair
gene silencing
Online Access:https://www.mdpi.com/2072-6694/12/11/3260

Internet

https://www.mdpi.com/2072-6694/12/11/3260

Similar Items