Prohibitins: A Critical Role in Mitochondrial Functions and Implication in Diseases

Prohibitin 1 (PHB1) and prohibitin 2 (PHB2) are proteins that are ubiquitously expressed, and are present in the nucleus, cytosol, and mitochondria. Depending on the cellular localization, PHB1 and PHB2 have distinctive functions, but more evidence suggests a critical role within mitochondria. In fa...

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Bibliographic Details
Main Authors: Anna Signorile, Giuseppe Sgaramella, Francesco Bellomo, Domenico De Rasmo
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Cells
Subjects:
Online Access:http://www.mdpi.com/2073-4409/8/1/71