Liquid–liquid phase separation of H3K27me3 reader BP1 regulates transcriptional repression
Abstract Background Bromo-adjacent homology-plant homeodomain domain containing protein 1 (BP1) is a reader of histone post-translational modifications in fungi. BP1 recognizes trimethylation of lysine 27 in histone H3 (H3K27me3), an epigenetic hallmark of gene silencing. However, whether and how BP...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2024-03-01
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| Series: | Genome Biology |
| Online Access: | https://doi.org/10.1186/s13059-024-03209-7 |