Liquid–liquid phase separation of H3K27me3 reader BP1 regulates transcriptional repression
Abstract Background Bromo-adjacent homology-plant homeodomain domain containing protein 1 (BP1) is a reader of histone post-translational modifications in fungi. BP1 recognizes trimethylation of lysine 27 in histone H3 (H3K27me3), an epigenetic hallmark of gene silencing. However, whether and how BP...
Main Authors: | Guangfei Tang, Haoxue Xia, Yufei Huang, Yuanwen Guo, Yun Chen, Zhonghua Ma, Wende Liu |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2024-03-01
|
Series: | Genome Biology |
Online Access: | https://doi.org/10.1186/s13059-024-03209-7 |
Similar Items
-
Repressive H3K27me3 drives hyperglycemia-induced oxidative and inflammatory transcriptional programs in human endothelium
by: Julia Sánchez-Ceinos, et al.
Published: (2024-04-01) -
The BAH domain of BAHD1 is a histone H3K27me3 reader
by: Dan Zhao, et al.
Published: (2016-02-01) -
Histone H3K27me3 methylation regulates the expression of secreted proteins distributed at fast-evolving regions through transcriptional repression of transposable elements
by: Jia-hui XIE, et al.
Published: (2023-10-01) -
ApoE maintains neuronal integrity via microRNA and H3K27me3-mediated repression
by: Jiazi Tan, et al.
Published: (2024-03-01) -
Peculiarity of transcriptional and H3K27me3 dynamics during peach bud dormancy
by: Yalin Zhao, et al.
Published: (2024-01-01)