HMGB1 and Toll-like receptors: potential therapeutic targets in autoimmune diseases
Abstract HMGB1, a nucleoprotein, is expressed in almost all eukaryotic cells. During cell activation and cell death, HMGB1 can function as an alarm protein (alarmin) or damage-associated molecular pattern (DAMP) and mediate early inflammatory and immune response when it is translocated to the extrac...
| Main Authors: | , , , , |
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| Format: | Article |
| Sprog: | English |
| Udgivet: |
BMC
2023-09-01
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| Serier: | Molecular Medicine |
| Fag: | |
| Online adgang: | https://doi.org/10.1186/s10020-023-00717-3 |