Exploring the role of Janus kinase (JAK) in atopic dermatitis: a review of molecular mechanisms and therapeutic strategies

AbstractRecent studies have demonstrated that Janus kinase (JAK) plays a crucial role in signal transduction by directly affecting various cytokine receptors involved in inflammatory diseases such as atopic dermatitis (AD). Large-scale clinical trials on AD utilizing JAK inhibitors and biologic reag...

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Bibliographic Details
Main Authors: Toshiaki Kogame, Gyohei Egawa, Kenji Kabashima
Format: Article
Language:English
Published: Taylor & Francis Group 2023-07-01
Series:Immunological Medicine
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/25785826.2023.2214324