The proteome of the blood–brain barrier in rat and mouse: highly specific identification of proteins on the luminal surface of brain microvessels by in vivo glycocapture

Abstract Background The active transport of molecules into the brain from blood is regulated by receptors, transporters, and other cell surface proteins that are present on the luminal surface of endothelial cells at the blood–brain barrier (BBB). However, proteomic profiling of proteins present on...

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Bibliographic Details
Main Authors: Tammy-Lynn Tremblay, Wael Alata, Jacqueline Slinn, Ewa Baumann, Christie E. Delaney, Maria Moreno, Arsalan S. Haqqani, Danica B. Stanimirovic, Jennifer J. Hill
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Fluids and Barriers of the CNS
Subjects:
Online Access:https://doi.org/10.1186/s12987-024-00523-x