Pooled analysis of frontal lobe transcriptomic data identifies key mitophagy gene changes in Alzheimer's disease brain

Pooled analysis of frontal lobe transcriptomic data identifies key mitophagy gene changes in Alzheimer's disease brain

BackgroundThe growing prevalence of Alzheimer's disease (AD) is becoming a global health challenge without effective treatments. Defective mitochondrial function and mitophagy have recently been suggested as etiological factors in AD, in association with abnormalities in components of the autop...

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Bibliographic Details
Main Authors: Taoyu Mei, Yuan Li, Anna Orduña Dolado, Zhiquan Li, Robin Andersson, Laura Berliocchi, Lene Juel Rasmussen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Aging Neuroscience
Subjects:
Alzheimer's disease
mitochondria
mitophagy
lysosome
transcriptomics
VCP
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2023.1101216/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2023.1101216/full

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