Actomyosin-dependent cortical dynamics contributes to the prophase force-balance in the early Drosophila embryo.

The assembly of the Drosophila embryo mitotic spindle during prophase depends upon a balance of outward forces generated by cortical dynein and inward forces generated by kinesin-14 and nuclear elasticity. Myosin II is known to contribute to the dynamics of the cell cortex but how this influences th...

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Bibliographic Details
Main Authors: Patrizia Sommi, Dhanya Cheerambathur, Ingrid Brust-Mascher, Alex Mogilner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3069073?pdf=render