Improved osteogenic differentiation of umbilical cord blood MSCs using custom made perfusion bioreactor

Background: 3D cell culture is an appropriate method to develop engineered bone tissue, where different bioreactors have been designed to mitigate the challenges in 3D culture. Currently, we tailored a perfusion reactor to witness human mesenchymal stem cells (MSCs) proliferation and differentiation...

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Bibliographic Details
Main Authors: Bhaskar Birru, Naveen Kumar Mekala, Sreenivasa Rao Parcha
Format: Article
Language:English
Published: Elsevier 2018-10-01
Series:Biomedical Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S2319417017303499