Dexmedetomidine attenuates inflammation and organ injury partially by upregulating Nur77 in sepsis

Abstract Purpose The aim of this study was to investigate the effect of dexmedetomidine (Dex) on inflammation and organ injury in sepsis, as well as the potential relationship between Dex and nuclear receptor 77 (Nur77). Methods We investigated the effects of dexmedetomidine on lipopolysaccharide (L...

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Bibliographic Details
Main Authors: Qian Zhang, Yun Huang, Chenchen Gong, Yan Tang, Jie Xiong, Difen Wang, Xu Liu
Format: Article
Language:English
Published: Wiley 2023-06-01
Series:Immunity, Inflammation and Disease
Subjects:
Online Access:https://doi.org/10.1002/iid3.883