Preparation and in vivo evaluation of a gel-based nasal delivery system for risperidone

The aim of this study was to prepare a nasal gel of risperidone and to investigate the pharmacokinetics and relative bioavailability of the drug in rats. Compared with oral dosing, the risperidone nasal gel exhibited very fast absorption and high bioavailability. Maximal plasma concentration (cmax)...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Gu Fugen, Ma Weina, Meng Gendalai, Wu Chunzhi, Wang Yi
Format: Artikel
Sprache:English
Veröffentlicht: Sciendo 2016-12-01
Schriftenreihe:Acta Pharmaceutica
Schlagworte:
Online Zugang:https://doi.org/10.1515/acph-2016-0047