Prediction models for hormone receptor status in female breast cancer do not extend to males: further evidence of sex-based disparity in breast cancer

Abstract Breast cancer prognosis and management for both men and women are reliant upon estrogen receptor alpha (ERα) and progesterone receptor (PR) expression to inform therapy. Previous studies have shown that there are sex-specific binding characteristics of ERα and PR in breast cancer and, count...

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Bibliographic Details
Main Authors: Subarnarekha Chatterji, Jan Moritz Niehues, Marko van Treeck, Chiara Maria Lavinia Loeffler, Oliver Lester Saldanha, Gregory Patrick Veldhuizen, Didem Cifci, Zunamys Itzell Carrero, Rasha Abu-Eid, Valerie Speirs, Jakob Nikolas Kather
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:npj Breast Cancer
Online Access:https://doi.org/10.1038/s41523-023-00599-y