Screening and Isolation of Potential Anti-Inflammatory Compounds from <i>Saxifraga atrata</i> via Affinity Ultrafiltration-HPLC and Multi-Target Molecular Docking Analyses

Screening and Isolation of Potential Anti-Inflammatory Compounds from <i>Saxifraga atrata</i> via Affinity Ultrafiltration-HPLC and Multi-Target Molecular Docking Analyses

In this study, a 100 g sample of <i>Saxifraga atrata</i> was processed to separate 1.3 g of 11-O-(4′-O-methylgalloyl)-bergenin (Fr1) after 1 cycle of MCI GEL<sup>®</sup> CHP20P medium pressure liquid chromatography using methanol/water. Subsequently, COX-2 affinity ultrafiltr...

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Bibliographic Details
Main Authors: Gang Li, Yan Fang, Yonggui Ma, Yangzom Dawa, Qilan Wang, Jing Gan, Jun Dang
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Nutrients
Subjects:
affinity ultrafiltration
molecular docking
preparative isolation
<i>Saxifraga atrata</i>
11-O-(4′-O-methylgalloyl)-bergenin
Online Access:https://www.mdpi.com/2072-6643/14/12/2405

Internet

https://www.mdpi.com/2072-6643/14/12/2405

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