Role of prolyl hydroxylase domain proteins in bone metabolism

Role of prolyl hydroxylase domain proteins in bone metabolism

Cellular metabolism requires dissolved oxygen gas. Because evolutionary refinements have constrained mammalian dissolved oxygen levels, intracellular oxygen sensors are vital for optimizing the bioenergetic and biosynthetic use of dissolved oxygen. Prolyl hydroxylase domain (PHD) homologs 1–3 (PHD1/...

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Bibliographic Details
Main Authors: David Wolf, Aruljothi Muralidharan, Subburaman Mohan
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:Osteoporosis and Sarcopenia
Subjects:
Bone
Prolyl hydroxylase domain
Hypoxia-inducible factor
Bone regeneration
Oxygen sensor
Epigenetic regulation
Online Access:http://www.sciencedirect.com/science/article/pii/S2405525522000036

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http://www.sciencedirect.com/science/article/pii/S2405525522000036

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