Fibrinogen-like protein 1 (FGL1): the next immune checkpoint target

Abstract Immune checkpoint therapy has achieved significant efficacy by blocking inhibitory pathways to release the function of T lymphocytes. In the clinic, anti-programmed cell death protein 1/programmed cell death ligand 1 (PD-1/PD-L1) monoclonal antibodies (mAbs) have progressed to first-line mo...

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Bibliographic Details
Main Authors: Wenjing Qian, Mingfang Zhao, Ruoyu Wang, Heming Li
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Journal of Hematology & Oncology
Subjects:
Online Access:https://doi.org/10.1186/s13045-021-01161-8