STING Agonist‐Loaded Nanoparticles Promotes Positive Regulation of Type I Interferon‐Dependent Radioimmunotherapy in Rectal Cancer

STING Agonist‐Loaded Nanoparticles Promotes Positive Regulation of Type I Interferon‐Dependent Radioimmunotherapy in Rectal Cancer

Abstract Hypoxia‐associated radioresistance in rectal cancer (RC) has severely hampered the response to radioimmunotherapy (iRT), necessitating innovative strategies to enhance RC radiosensitivity and improve iRT efficacy. Here, a catalytic radiosensitizer, DMPtNPS, and a STING agonist, cGAMP, are i...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Lei Wang, Han Zhou, Qingjing Chen, Zhiwen Lin, Chenwei Jiang, Xingte Chen, Mingdong Chen, Libin Liu, Lingdong Shao, Xiaolong Liu, Jianji Pan, Jingcheng Wu, Jibin Song, Junxin Wu, Da Zhang
स्वरूप: लेख
भाषा:English
प्रकाशित: Wiley 2024-02-01
श्रृंखला:Advanced Science
विषय:
cGAMP
hypoxia
platinum nanoparticles
radioimmunotherapy
radiosensitizers
ऑनलाइन पहुंच:https://doi.org/10.1002/advs.202307858

इंटरनेट

https://doi.org/10.1002/advs.202307858

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