Shank2 identifies a subset of glycinergic neurons involved in altered nociception in an autism model

Shank2 identifies a subset of glycinergic neurons involved in altered nociception in an autism model

Abstract Background Autism Spectrum Disorders (ASD) patients experience disturbed nociception in the form of either hyposensitivity to pain or allodynia. A substantial amount of processing of somatosensory and nociceptive stimulus takes place in the dorsal spinal cord. However, many of these circuit...

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Bibliographic Details
Main Authors: Florian Olde Heuvel, Najwa Ouali Alami, Oumayma Aousji, Esther Pogatzki-Zahn, Peter K. Zahn, Hanna Wilhelm, Dhruva Deshpande, Elmira Khatamsaz, Alberto Catanese, Sarah Woelfle, Michael Schön, Sanjay Jain, Stefanie Grabrucker, Albert C. Ludolph, Chiara Verpelli, Jens Michaelis, Tobias M. Boeckers, Francesco Roselli
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Molecular Autism
Subjects:
Shank2
Autism spectrum disorder
Nociception
Spinal cord
Glycinergic interneurons
Online Access:https://doi.org/10.1186/s13229-023-00552-7

Internet

https://doi.org/10.1186/s13229-023-00552-7

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