Age-cumulative effect of REC8 reduction on meiotic chromosome segregation errors in mice

Age-cumulative effect of REC8 reduction on meiotic chromosome segregation errors in mice

Objective: This study aimed to explore the relationship between cohesin subunit REC8 reduction and meiosis chromosome segregation errors in the ovary. Methods: Rec8+/− mice were generated using CRIPSR/Cas9 gene editing. The association between age and REC8 expression levels in the ovary was determin...

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Bibliographic Details
Main Authors: Li-Yuan Tian, Ling Zhang, Cheng-Qiu Tao, Xiao-Qi Lin, Feng Zhang, Bin Zhang
Format: Article
Language:English
Published: Wolters Kluwer Health/LWW 2021-01-01
Series:Reproductive and Developmental Medicine
Subjects:
chromosome segregation errors; cohesin; meiosis; rec8
Online Access:http://www.repdevmed.org/article.asp?issn=2096-2924;year=2021;volume=5;issue=4;spage=193;epage=198;aulast=Tian

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http://www.repdevmed.org/article.asp?issn=2096-2924;year=2021;volume=5;issue=4;spage=193;epage=198;aulast=Tian

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