HIPK1 Inhibition Protects against Pathological Cardiac Hypertrophy by Inhibiting the CREB‐C/EBPβ Axis

HIPK1 Inhibition Protects against Pathological Cardiac Hypertrophy by Inhibiting the CREB‐C/EBPβ Axis

Abstract Inhibition of pathological cardiac hypertrophy is recognized as an important therapeutic strategy for heart failure, although effective targets are still lacking in clinical practice. Homeodomain interacting protein kinase 1 (HIPK1) is a conserved serine/threonine kinase that can respond to...

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Bibliographic Details
Main Authors: Yihua Bei, Yujiao Zhu, Meng Wei, Mingming Yin, Lin Li, Chen Chen, Zhenzhen Huang, Xuchun Liang, Juan Gao, Jianhua Yao, Petra H. van derKraak, Aryan Vink, Zhiyong Lei, Yuxiang Dai, Huihua Chen, Yueyang Liang, Joost PG Sluijter, Junjie Xiao
Format: Article
Language:English
Published: Wiley 2023-06-01
Series:Advanced Science
Subjects:
C/EBPβ
cardiomyocytes
CREB
HIPK1
pathological hypertrophy
Online Access:https://doi.org/10.1002/advs.202300585

Internet

https://doi.org/10.1002/advs.202300585

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