Potential utility of risk stratification for multicancer screening with liquid biopsy tests

Abstract Our proof-of-concept study reveals the potential of risk stratification by the combined effects of age, polygenic risk scores (PRS), and non-genetic risk factors in increasing the risk-benefit balance of rapidly emerging non-invasive multicancer early detection (MCED) liquid biopsy tests. W...

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Bibliographic Details
Main Authors: Elle S. Kim, Robert B. Scharpf, Montserrat Garcia-Closas, Kala Visvanathan, Victor E. Velculescu, Nilanjan Chatterjee
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-023-00377-w