Sumoylation promotes optimal APC/C activation and timely anaphase
The Anaphase Promoting Complex/Cyclosome (APC/C) is a ubiquitin E3 ligase that functions as the gatekeeper to mitotic exit. APC/C activity is controlled by an interplay of multiple pathways during mitosis, including the spindle assembly checkpoint (SAC), that are not yet fully understood. Here, we s...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2018-03-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/29539 |