Role of the Nlrp3 Inflammasome in Microbial Infection

The intracellular Nod-like receptor Nlrp3 has emerged as the most versatile innate immune receptor because of its broad specificity in mediating immune response to a wide range of microbial or danger signals. Nlrp3 mediates assembly of the inflammasome complex in the presence of microbial components...

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Bibliographic Details
Main Authors: Paras K Anand, R.K. Subbarao eMalireddi, Thirumala-Devi eKanneganti
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-02-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2011.00012/full