Collecting and deactivating TGF-β1 hydrogel for anti-scarring therapy in post-glaucoma filtration surgery

Collecting and deactivating TGF-β1 hydrogel for anti-scarring therapy in post-glaucoma filtration surgery

Scar formation can lead to glaucoma filtration surgery (GFS) failure, wherein transforming growth factor (TGF)-β is the core regulator. To reducing scar formation, this paper presents our study on the design of hydrogels to deactivate TGF-β1. We hypothesized that excess TGF-β1 can be removed from aq...

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Bibliographic Details
Main Authors: Ruiqi Wang, Boyang Chen, Haiying Wei, Wei Yan, Yuping Wu, Cao Wang, Bosong Zhang, Fengzhen Liu, Hui Tian, Xiongbiao Chen, Weiming Tian
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:Materials Today Bio
Subjects:
Glaucoma filtration surgery
TGF-β1
Decorin
anti-scarring therapy
Hydrogel
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006422000588

Internet

http://www.sciencedirect.com/science/article/pii/S2590006422000588

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