Translational selection is ubiquitous in prokaryotes.

Codon usage bias in prokaryotic genomes is largely a consequence of background substitution patterns in DNA, but highly expressed genes may show a preference towards codons that enable more efficient and/or accurate translation. We introduce a novel approach based on supervised machine learning that...

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Bibliographic Details
Main Authors: Fran Supek, Nives Skunca, Jelena Repar, Kristian Vlahovicek, Tomislav Smuc
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-06-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2891978?pdf=render