Duchenne muscular dystrophy disease severity impacts skeletal muscle progenitor cells systemic delivery

Duchenne muscular dystrophy (DMD) is caused by an out-of-frame mutation in the DMD gene that results in the absence of a functional dystrophin protein, leading to a devastating progressive lethal muscle-wasting disease. Muscle stem cell-based therapy is a promising avenue for improving muscle regene...

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Bibliographic Details
Main Authors: Kholoud K. Saleh, Corey Switzler, Michael R. Hicks, Lily Gane, Devin E. Gibbs, April D. Pyle
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1190524/full