Duchenne muscular dystrophy disease severity impacts skeletal muscle progenitor cells systemic delivery
Duchenne muscular dystrophy (DMD) is caused by an out-of-frame mutation in the DMD gene that results in the absence of a functional dystrophin protein, leading to a devastating progressive lethal muscle-wasting disease. Muscle stem cell-based therapy is a promising avenue for improving muscle regene...
Main Authors: | Kholoud K. Saleh, Corey Switzler, Michael R. Hicks, Lily Gane, Devin E. Gibbs, April D. Pyle |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2023-05-01
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Series: | Frontiers in Physiology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fphys.2023.1190524/full |
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