Replenishable prevascularized cell encapsulation devices increase graft survival and function in the subcutaneous space

Abstract Beta cell replacement therapy (BCRT) for patients with type 1 diabetes (T1D) improves blood glucose regulation by replenishing the endogenous beta cells destroyed by autoimmune attack. Several limitations, including immune isolation, prevent this therapy from reaching its full potential. Ce...

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Bibliographic Details
Main Authors: Gauree S. Chendke, Bhushan N. Kharbikar, Sudipta Ashe, Gaetano Faleo, Julie B. Sneddon, Qizhi Tang, Matthias Hebrok, Tejal A. Desai
Format: Article
Language:English
Published: Wiley 2023-07-01
Series:Bioengineering & Translational Medicine
Subjects:
Online Access:https://doi.org/10.1002/btm2.10520