Environmental enrichment increases hippocampal glucocorticoid receptors and decreases GluA2 and protein kinase M zeta (PKMz) trafficking during chronic stress: A protective mechanism?

Environmental enrichment increases hippocampal glucocorticoid receptors and decreases GluA2 and protein kinase M zeta (PKMz) trafficking during chronic stress: A protective mechanism?

Environmental enrichment (EE) housing paradigms have long been shown beneficial for brain function involving neural growth and activity, learning and memory capacity, and for developing stress resiliency. The expression of the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor sub...

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Bibliographic Details
Main Authors: Roseanna M Zanca, Stephen eBraren, Brigid eMaloney, Lisa eSchrott, Victoria eLuine, Peter eSerrano
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-11-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Corticosterone
Hippocampus
Stress, Psychological
environmental enrichment
PKMzeta
forced swim test
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2015.00303/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnbeh.2015.00303/full

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