High frequency of BRCA1, but not CHEK2 or NBS1 (NBN), founder mutations in Russian ovarian cancer patients

High frequency of BRCA1, but not CHEK2 or NBS1 (NBN), founder mutations in Russian ovarian cancer patients

<p>Abstract</p> <p>Background</p> <p>A significant portion of ovarian cancer (OC) cases is caused by germ-line mutations in BRCA1 or BRCA2 genes. BRCA testing is cheap in populations with founder effect and therefore recommended for all patients with OC diagnosis. Recur...

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Bibliographic Details
Main Authors: Suspitsin Evgeny N, Sherina Nathalia, Ponomariova Daria N, Sokolenko Anna P, Iyevleva Aglaya G, Gorodnova Tatyana V, Zaitseva Olga A, Yatsuk Olga S, Togo Alexandr V, Tkachenko Nathalia N, Shiyanov Grigory A, Lobeiko Oksana S, Krylova Nadezhda, Matsko Dmitry E, Maximov Sergey, Urmancheyeva Adel F, Porhanova Nathalia V, Imyanitov Evgeny N
Format: Article
Language:English
Published: BMC 2009-02-01
Series:Hereditary Cancer in Clinical Practice
Online Access:http://www.hccpjournal.com/content/7/1/5

Internet

http://www.hccpjournal.com/content/7/1/5

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