Role of p53 in Regulating Radiation Responses

p53 is known as the guardian of the genome and plays various roles in DNA damage and cancer suppression. The <i>p53</i> gene was found to express multiple p53 splice variants (isoforms) in a physiological, tissue-dependent manner. The various genes that up- and down-regulated p53 are inv...

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Bibliographic Details
Main Author: Ryuji Okazaki
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/12/7/1099