miR-182-5p Regulates Nogo-A Expression and Promotes Neurite Outgrowth of Hippocampal Neurons In Vitro

miR-182-5p Regulates Nogo-A Expression and Promotes Neurite Outgrowth of Hippocampal Neurons In Vitro

Nogo-A protein is a key myelin-associated inhibitor of axonal growth, regeneration, and plasticity in the central nervous system (CNS). Regulation of the Nogo-A/NgR1 pathway facilitates functional recovery and neural repair after spinal cord trauma and ischemic stroke. MicroRNAs are described as eff...

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Bibliographic Details
Main Authors: Altea Soto, Manuel Nieto-Díaz, David Reigada, María Asunción Barreda-Manso, Teresa Muñoz-Galdeano, Rodrigo M. Maza
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Pharmaceuticals
Subjects:
miR-182-5p
Nogo-A
neurite outgrowth
axonal regeneration
spinal cord injury
neurodegenerative diseases
Online Access:https://www.mdpi.com/1424-8247/15/5/529

Internet

https://www.mdpi.com/1424-8247/15/5/529

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