Glabridin improves autoimmune disease in Trex1-deficient mice by reducing type I interferon production

Glabridin improves autoimmune disease in Trex1-deficient mice by reducing type I interferon production

Abstract Background The cGAS-STING signaling pathway is an essential section of the natural immune system. In recent years, an increasing number of studies have shown a strong link between abnormal activation of the cGAS-STING signaling pathway, a natural immune pathway mediated by the nucleic acid...

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Bibliographic Details
Main Authors: Jincai Wen, Wenqing Mu, Hui Li, Yulu Yan, Xiaoyan Zhan, Wei Luo, Zhongxia Wang, Wen Kan, Jia Zhao, Siwen Hui, Ping He, Shuanglin Qin, Yingjie Xu, Ping Zhang, Xiaohe Xiao, Guang Xu, Zhaofang Bai
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Molecular Medicine
Subjects:
Glabridin
cGAS-STING
IRF3
Autoimmune diseases
Type I interferon
Online Access:https://doi.org/10.1186/s10020-023-00754-y

Internet

https://doi.org/10.1186/s10020-023-00754-y

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