Benzodiazepine receptor ligand influences on learning: an endogenous modulatory mechanism mediated by benzodiazepines possibly of alimentary origin

Benzodiazepine receptor ligand influences on learning: an endogenous modulatory mechanism mediated by benzodiazepines possibly of alimentary origin

In rats pre-but not post-training ip administration of either flumazenil, a central benzodiazepine (BSD) receptor antagonist, or of n-butyl-B-carboline-carboxylate (BCCB), an inverse agonist, enhanced retention of inhibitory avoidance learning. Flumazenil vlocked the enhancing effect of BCCB, and th...

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Bibliographic Details
Main Authors: I. Izquierdo, M. E. Pereira, C. da Cunha, C. Wolfman, J. H. Medina
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 1991-01-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
learning
memory formation
endogenous benzodiazepines
flumazenil
benzodiazepine receptor ligands
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761991000600038

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761991000600038

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