Expression and Polymorphism of Toll-Like Receptor 4 and Effect on NF-κB Mediated Inflammation in Colon Cancer Patients.

Our aim was to evaluate the association between the expression and the polymorphism of TLR4/NF-κB pathways and colon cancer. TLR4 (rs4986790, rs10759932, rs10759931 and rs2770150) were genotyped in blood samples from Colorectal patients and healthy controls. TLR4 and cytokines inflammatory expressio...

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Bibliographic Details
Main Authors: Abdelhabib Semlali, Narasimha Reddy Parine, Maha Arafah, Lamjed Mansour, Arezki Azzi, Omair Al Shahrani, Abdullah Al Amri, Jilani P Shaik, Abdulrahman M Aljebreen, Othman Alharbi, Majid A Almadi, Nahla Ali Azzam, Muhammad Kohailan, Mahmoud Rouabhia, Mohammad Saud Alanazi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4714746?pdf=render