Focused ultrasound neuromodulation of the spleen activates an anti-inflammatory response in humans

Focused ultrasound neuromodulation of the spleen activates an anti-inflammatory response in humans

Focused ultrasound stimulation (FUS) activates mechanosensitive ion channels and is emerging as a method of noninvasive neuromodulation. In preclinical studies, FUS of the spleen (sFUS) activates an anti-inflammatory neural pathway which suppresses acute and chronic inflammation. However, the releva...

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Bibliographic Details
Main Authors: Stavros Zanos, Despoina Ntiloudi, John Pellerito, Richard Ramdeo, John Graf, Kirk Wallace, Victoria Cotero, Jeff Ashe, Jessica Moon, Meghan Addorisio, David Shoudy, Thomas R. Coleman, Michael Brines, Chris Puleo, Kevin J. Tracey, Sangeeta S. Chavan
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Brain Stimulation
Subjects:
Inflammation
Cytokines
Ultrasound
Spleen
Cholinergic anti-inflammatory pathway
Bioelectronic medicine
Online Access:http://www.sciencedirect.com/science/article/pii/S1935861X23017436

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http://www.sciencedirect.com/science/article/pii/S1935861X23017436

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