Essential site scanning analysis: A new approach for detecting sites that modulate the dispersion of protein global motions

Despite the wealth of methods developed for exploring the molecular basis of allostery in biomolecular systems, there is still a need for structure-based predictive tools that can efficiently detect susceptible sites for triggering allosteric responses. Toward this goal, we introduce here an elastic...

Full description

Bibliographic Details
Main Authors: Burak T. Kaynak, Ivet Bahar, Pemra Doruker
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037020303093