Transcriptional landscape and clinical utility of enhancer RNAs for eRNA-targeted therapy in cancer

Enhancer RNA (eRNA) is a type of noncoding RNA transcribed from enhancer regions. Here, the authors investigate the transcriptional landscape of eRNA in cancer, incorporating pharmacogenomic data to identify potential target genes and therapeutic targets.

Bibliographic Details
Main Authors: Zhao Zhang, Joo-Hyung Lee, Hang Ruan, Youqiong Ye, Joanna Krakowiak, Qingsong Hu, Yu Xiang, Jing Gong, Bingying Zhou, Li Wang, Chunru Lin, Lixia Diao, Gordon B. Mills, Wenbo Li, Leng Han
Format: Article
Language:English
Published: Nature Portfolio 2019-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-12543-5