Proteomic, mechanical, and biochemical development of tissue-engineered neocartilage

Abstract Background The self-assembling process of cartilage tissue engineering is a promising technique to heal cartilage defects, preventing osteoarthritic changes. Given that chondrocytes dedifferentiate when expanded, it is not known if cellular expansion affects the development of self-assemble...

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Bibliographic Details
Main Authors: Benjamin J. Bielajew, Ryan P. Donahue, Elliott K. Lamkin, Jerry C. Hu, Vincent C. Hascall, Kyriacos A. Athanasiou
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2022-07-01
Series:Biomaterials Research
Subjects:
Online Access:https://doi.org/10.1186/s40824-022-00284-4