Genomic insights into the evolution and mechanisms of carbapenem-resistant hypervirulent Klebsiella pneumoniae co-harboring bla KPC and bla NDM: implications for public health threat mitigation

Genomic insights into the evolution and mechanisms of carbapenem-resistant hypervirulent Klebsiella pneumoniae co-harboring bla KPC and bla NDM: implications for public health threat mitigation

Abstract Background Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP) co-producing bla KPC and bla NDM poses a serious threat to public health. This study aimed to investigate the mechanisms underlying the resistance and virulence of CR-hvKP isolates collected from a Chinese hospita...

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Bibliographic Details
Main Authors: Qian Wang, Yue Liu, Ran Chen, Meng Zhang, Zaifeng Si, Yueling Wang, Yan Jin, Yuanyuan Bai, Zhen Song, Xinglun Lu, Mingju Hao, Yingying Hao
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Annals of Clinical Microbiology and Antimicrobials
Subjects:
Bla KPC
Bla NDM
ST11-KL64
CR-HvKP
IncC-type plasmid
Online Access:https://doi.org/10.1186/s12941-024-00686-3

Internet

https://doi.org/10.1186/s12941-024-00686-3

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