Fluorogenic Aptamer-Based Hybridization Chain Reaction for Signal-Amplified Imaging of Apurinic/Apyrimidinic Endonuclease 1 in Living Cells

Fluorogenic Aptamer-Based Hybridization Chain Reaction for Signal-Amplified Imaging of Apurinic/Apyrimidinic Endonuclease 1 in Living Cells

A fluorogenic aptamer (FA)-based hybridization chain reaction (HCR) could provide a sensitive and label-free signal amplification method for imaging molecules in living cells. However, existing FA-HCR methods usually face some problems, such as a complicated design and significant background leakage...

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Bibliographic Details
Main Authors: Meixi Liu, Yunjie Tan, Chen Zhou, Zhaoming Fu, Ru Huang, Jin Li, Le Li
Format: Article
Language:English
Published: MDPI AG 2024-05-01
Series:Biosensors
Subjects:
fluorescence imaging
hybridization chain reaction
signal amplification
APE1
Online Access:https://www.mdpi.com/2079-6374/14/6/274

Internet

https://www.mdpi.com/2079-6374/14/6/274

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