Simulated-physiological loading conditions preserve biological and mechanical properties of caprine lumbar intervertebral discs in ex vivo culture.

Simulated-physiological loading conditions preserve biological and mechanical properties of caprine lumbar intervertebral discs in ex vivo culture.

Low-back pain (LBP) is a common medical complaint and associated with high societal costs. Degeneration of the intervertebral disc (IVD) is assumed to be an important causal factor of LBP. IVDs are continuously mechanically loaded and both positive and negative effects have been attributed to differ...

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Bibliographic Details
Main Authors: Cornelis P L Paul, Hendrik A Zuiderbaan, Behrouz Zandieh Doulabi, Albert J van der Veen, Peter M van de Ven, Theo H Smit, Marco N Helder, Barend J van Royen, Margriet G Mullender
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3302815?pdf=render

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http://europepmc.org/articles/PMC3302815?pdf=render

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