GAS6-based CAR-T cells exhibit potent antitumor activity against pancreatic cancer

Abstract Background The receptor tyrosine kinases TAM family (TYRO3, AXL, and MERTK) are highly expressed in multiple forms of cancer cells and tumor-associated macrophages and promote the development of cancers including pancreatic tumor. Targeting TAM receptors could be a promising therapeutic opt...

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书目详细资料
Main Authors: Jiawei Fan, Ye Yu, Lanzhen Yan, Yuncang Yuan, Bin Sun, Dong Yang, Nan Liu, Jing Guo, Jie Zhang, Xudong Zhao
格式: 文件
语言:English
出版: BMC 2023-07-01
丛编:Journal of Hematology & Oncology
主题:
在线阅读:https://doi.org/10.1186/s13045-023-01467-9