High efficiency preparation of monodisperse plasma membrane derived extracellular vesicles for therapeutic applications

Abstract Extracellular vesicles (EVs) are highly interesting for the design of next-generation therapeutics. However, their preparation methods face challenges in standardization, yield, and reproducibility. Here, we describe a highly efficient and reproducible EV preparation method for monodisperse...

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Bibliographic Details
Main Authors: Claudio L. Alter, Pascal Detampel, Roman B. Schefer, Claudia Lotter, Patrick Hauswirth, Ramya D. Puligilla, Vera J. Weibel, Susanne H. Schenk, Wolf Heusermann, Melanie Schürz, Nicole Meisner-Kober, Cornelia Palivan, Tomaž Einfalt, Jörg Huwyler
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-04859-2