The antitumor activity of hPRDX5 against pancreatic cancer and the possible mechanisms

Recombinant human peroxiredoxin-5 (hPRDX5), isolated from anti-cancer bioactive peptide (ACBPs), shows a homology of 89% with goat peroxiredoxin-5 (gPRDX5) and is reported to display anti-tumor activity in vivo. Herein, we explored the effect of hPRDX5 and the responsible mechanism in treating pancr...

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Bibliographic Details
Main Authors: Lihua Cui, Yuanyuan Jin, Sen Zou, Jing Xun, Xiangyang Yu, Qi Zhang, Zhaoyong Yang
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2022-09-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2022000100658&tlng=en